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Symbol
Name
ID 		Hand1
heart and neural crest derivatives expressed 1
MGI:103577
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal cardiovascular system morphology
absent vitelline blood vessels
abnormal myocardial trabeculae morphology
thin left ventricle myocardium compact layer
thin myocardium
abnormal cardiac outflow tract development
abnormal heart development
abnormal atrioventricular cushion morphology
abnormal heart looping
failure of heart looping
abnormal heart morphology
double outlet right ventricle
overriding aortic valve
abnormal heart apex morphology
abnormal atrioventricular valve morphology
abnormal heart septum morphology
abnormal interventricular septum morphology
perimembraneous ventricular septal defect
abnormal interventricular septum muscular part morphology
ventricular septal defect
enlarged heart
cardiac hypertrophy
ventricular hypoplasia
decreased heart left ventricle size
decreased heart right ventricle size
thin ventricular wall
hemopericardium
dilated heart
hemorrhage
Availability Mouse Genotype
Hand1tm1Eno/Hand1tm1Eno
Hand1tm1Jcc/Hand1tm1Jcc
Hand1tm2(Hand1)Abfi/Hand1tm2(Hand1)Abfi
Hand1tm2.1(Hand1)Abfi/Hand1tm2.1(Hand1)Abfi
Hand1tm2.1Jcc/Hand1tm2.1Jcc
Hand1tm1Jcc/Hand1tm2.1Jcc
Hand1tm2.1Jcc/Hand1+
Hand1tm1Eno/Hand1tm2Eno
Tg(Myh6-cre)2182Mds/0  (conditional)
Hand1tm1Eno/Hand1tm2Eno
Tg(Nkx2-5-cre)9Eno/0  (conditional)
Hand1tm5Abfi/Hand1+
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Hand1tm5Abfi/Hand1+
Tg(Myh6-cre)2182Mds/0  (conditional)
Hand1tm5Abfi/Hand1+
Tg(Mef2c-cre)2Blk/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory